Immediately interact with the downstream hippocampus

Using simultaneous TMS-fMRI, we showed that theta-burst stimulation targeting the hippocampal network causes an immediate impact on hippocampal activity during encoding, improving memory formation as indicated by enhanced later recollection (Hermiller et al., 2020; J Neuro), while rhythm- and location-control stimulation conditions had no such effects.

We are interested in further using this direct influence of noninvasive stimulation on hippocampal neural activity to understand how the theta-burst rhythm can influence various memory network dynamic and stages of long-term memory function.

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Network-targeted stimulation

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Theta-burst stimulation